Peptide Knowledge Base · Metabolic

5-Amino-1MQ: what it is, what the evidence says, and its real status

A non-peptide small-molecule NNMT inhibitor marketed for fat-cell metabolism, research-stage only.

Short version: not a peptide, a research-stage molecule sold online for fat metabolism, with no controlled human efficacy data. Education only; we capture the query and say what we don't know.

Can you actually get it?

Plain-English verdict: Education only.

Regulatory status: Research-only · Education only.

Not offered, education only. 5-Amino-1MQ is a research-stage NNMT inhibitor (not a peptide, not FDA-approved) with no controlled human efficacy data. We capture the query and make no weight-loss claim.

How does 5-Amino-1MQ work?

A small-molecule inhibitor of NNMT (nicotinamide N-methyltransferase), proposed to shift fat-cell energy metabolism.

What it does — and what it does not do

What it does: Studied preclinically for fat-cell metabolism.

What it does not do: It is not a peptide, not proven in humans, and not a weight-loss treatment.

How honest is the evidence?

Evidence grade D — preclinical / animal-dominant; no controlled human efficacy data. Read our grading methodology for what each grade means.

What we still don't know: No credible controlled human evidence of meaningful fat loss; safety uncharacterized.

WADA status: Not prohibited.

How it is taken

Not offered; education only.

Who should not take it

Not characterized for human use; not a weight-loss treatment.

Sources

Preclinical NNMT-inhibition literature (animal-dominant)

Compounded medications are not FDA-approved. We keep two signals separate and never collapse them: whether you can get something, and what the rule currently says. See the live FDA Peptide Tracker or the knowledge base.

Join the founding list →

Last reviewed 2026-08-11 · Peptós.LIFE · Not medical advice.