Peptide Knowledge Base · Metabolic

5-Amino-1MQ: what it is, what the evidence says, and its real status

Not a peptide, a research-stage molecule sold online for fat metabolism, with no controlled human efficacy data.

Can you actually get it?

Plain-English verdict: No availability record.

Regulatory status: No regulatory record.

How does 5-Amino-1MQ work?

A small-molecule inhibitor of NNMT (nicotinamide N-methyltransferase), proposed to shift fat-cell energy metabolism.

What it does — and what it does not do

What it does: Studied preclinically for fat-cell metabolism.

What it does not do: It is not a peptide, not proven in humans, and not a weight-loss treatment.

How honest is the evidence?

Evidence grade D — Animal and lab evidence; human trials still to come.

preclinical / animal-dominant; no controlled human efficacy data

A grade measures how much human evidence exists, not whether a molecule is good, safe, or worth your interest. Read our grading methodology for what each grade means.

What we still don't know: No credible controlled human evidence of meaningful fat loss; safety uncharacterized.

WADA status: Not prohibited.

Who should not take it

Not characterized for human use; not a weight-loss treatment.

Sources

Preclinical NNMT-inhibition literature (animal-dominant)

Compounded medications are not FDA-approved. We keep two signals separate and never collapse them: whether you can get something, and what the rule currently says. See the live FDA Peptide Tracker for status.

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Last reviewed Jun 18, 2026 · Peptós.LIFE · Not medical advice.