Peptide Knowledge Base · GH-axis

Hexarelin: what it is, what the evidence says, and its real status

An older, potent GH-releasing peptide with real downsides (prolactin, receptor desensitization).

Can you actually get it?

Plain-English verdict: No availability record.

Regulatory status: No regulatory record.

How does Hexarelin work?

A potent ghrelin-receptor agonist that triggers a strong pulse of growth-hormone release.

What it does — and what it does not do

What it does: Raises growth hormone strongly; used historically in performance circles.

What it does not do: It is not approved or available, and tolerance plus prolactin effects limit its usefulness.

How honest is the evidence?

Evidence grade C — Mixed / early human evidence.

older human GH data; desensitization and prolactin concerns

A grade measures how much human evidence exists, not whether a molecule is good, safe, or worth your interest. Read our grading methodology for what each grade means.

What we still don't know: Long-term endocrine effects and the desensitization curve are poorly characterized.

WADA status: Banned (S2).

Who should not take it

WADA S2 banned; prolactin elevation; not characterized for safe human use.

Sources

Hexarelin GH-secretagogue literature; WADA Prohibited List

Compounded medications are not FDA-approved. We keep two signals separate and never collapse them: whether you can get something, and what the rule currently says. See the live FDA Peptide Tracker for status.

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Last reviewed Jun 18, 2026 · Peptós.LIFE · Not medical advice.