Peptide Knowledge Base · Recovery

IGF-1 LR3: what it is, what the evidence says, and its real status

A potent long-acting IGF-1 analog from the bodybuilding world. Powerful growth signaling means real risk, it is WADA-banned and research-only. Education and caution, never an offer.

Can you actually get it?

Plain-English verdict: No availability record.

Regulatory status: No regulatory record.

How does IGF-1 LR3 work?

A modified, long-acting form of insulin-like growth factor 1 that sustains anabolic and proliferative signaling in tissue.

What it does — and what it does not do

What it does: Drives muscle growth and recovery signaling; used illicitly in performance circles.

What it does not do: It is not approved, not safe to obtain, and not appropriate for anyone, its growth signaling is the risk.

How honest is the evidence?

Evidence grade D — Animal and lab evidence; human trials still to come.

research-only; potent growth signaling; human safety uncharacterized

A grade measures how much human evidence exists, not whether a molecule is good, safe, or worth your interest. Read our grading methodology for what each grade means.

What we still don't know: Long-term cancer-risk and metabolic effects of sustained IGF signaling are the central uncharacterized concerns.

WADA status: Banned (S2).

Who should not take it

Theoretical growth-promotion / cancer risk; WADA S2 banned; not characterized for safe human use.

Sources

IGF-1 / IGF-1 LR3 growth-factor literature; WADA Prohibited List

Compounded medications are not FDA-approved. We keep two signals separate and never collapse them: whether you can get something, and what the rule currently says. See the live FDA Peptide Tracker for status.

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Last reviewed Jun 18, 2026 · Peptós.LIFE · Not medical advice.