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The Canon

The go-to library for everything peptide.

The best of the open web on peptides, the papers, lectures, registries, and researchers we'd send a smart friend to. Vetted, dated, re-checked. Authoritative sources only: never a vendor, never a grey-market seller, never a dosing how-to.

24 references5 kindsWe link, we don't endorse

We link, we don't endorse. Peptós.LIFE curates these as educational references. A link is not an endorsement of any product, protocol, or dose, and never an instruction to self-administer. Compounded peptides are not FDA-approved.

Read

Primary literature + high-quality explainer journalism.

ReadBPC-157 cytoprotection & tissue-repair literature (review set)Journal of Physiology & Pharmacology · PubMed · Sikirić P, et al.The core body of preclinical work behind nearly every BPC-157 claim, overwhelmingly animal models, which is exactly why we grade it D.Last checked 2026-06-12 ReadThymosin β4 in tissue repair (the molecule TB-500 fragments)Annals of the NY Academy of Sciences · PubMed · Goldstein AL, et al.The legitimate science is on full-length thymosin β4, useful for seeing how far the marketed 'TB-500' fragment sits from trial-grade material.Last checked 2026-06-12 ReadGHK-Cu: regenerative & skin-remodeling actions (review)Int. J. Molecular Sciences · PubMed · Pickart L, Margolina AThe foundational copper-peptide review. Note it concerns topical/cosmetic and cell-culture work, not the injectable claims we keep separate.Last checked 2026-06-12 ReadNAD+ metabolism in ageing & disease (review)Nature Reviews Mol. Cell Biology · PubMed · Covarrubias AJ, Verdin E, et al.The serious mechanistic review of NAD+ biology, and a clear-eyed account of how early the human longevity evidence still is.Last checked 2026-06-12 ReadSermorelin & GHRH-analog clinical literaturePubMed · Multiple investigatorsThe clinical record behind the legal GH-axis answer, including its FDA-labeling history as the discontinued drug Geref.Last checked 2026-06-12 ReadTesamorelin pivotal trials (FDA-approved GHRH analog)New England Journal of Medicine · PubMed · Falutz J, et al.The strongest evidence pedigree in the GH-axis group, randomized human trials behind the approved product (Egrifta).Last checked 2026-06-12 ReadBremelanotide (PT-141) phase-3 trials for desireObstetrics & Gynecology · PubMed · Clayton AH, et al.The randomized human evidence behind PT-141, the rare research-peptide story with an FDA-approved counterpart (Vyleesi).Last checked 2026-06-12 ReadMOTS-c: a mitochondrial-derived regulator of metabolismCell Metabolism · PubMed · Lee C, et al.The foundational MOTS-c biology. Fascinating mechanism, almost entirely preclinical, the basis for its grade-D, waitlist position.Last checked 2026-06-12 ReadEpitalon / pineal-peptide regulation studiesPubMed · Khavinson VK, et al.The original (older, methodologically limited) work behind epitalon's bold longevity folklore, read it to see where the claims outrun the data.Last checked 2026-06-12 ReadSemaglutide weight-management trials (STEP program)NEJM / JAMA · PubMed · Wilding JPH, et al.Grade-A human evidence, large randomized trials. The honest contrast with the research peptides everyone lumps in with 'peptides.'Last checked 2026-06-12 ReadTirzepatide weight & metabolic trials (SURMOUNT / SURPASS)NEJM · PubMed · Jastreboff AM, et al.The strongest efficacy data in the category, from randomized human trials, the evidence bar everything else is measured against.Last checked 2026-06-12 ReadRapamycin, mTOR, and lifespan (review set)Nature / Science of Aging · PubMed · Multiple investigatorsThe mechanistic and animal-lifespan evidence behind rapamycin, strong across model organisms, still early in humans, which is exactly why we grade it B and gate it behind a clinician.Last checked 2026-06-12 ReadMetformin and the TAME trial (Targeting Aging with Metformin)PubMed · Cell Metabolism · Barzilai N, et al.The framing behind metformin's longevity hypothesis and the trial designed to test it, the honest line between 'proven for diabetes' and 'still being tested for aging.'Last checked 2026-06-12

Watch

Authoritative video explainers, lectures, credentialed interviews.

WatchHuberman Lab, peptides for health, performance & longevityHuberman Lab · Andrew Huberman, PhD · Neuroscientist · Stanford School of MedicineA long-form, mechanism-level overview from a credentialed academic host. Useful framing; we still hold its claims to our own evidence grades.Last checked 2026-06-12

Listen

Vetted audio, credentialed-host science podcasts.

ListenThe Peter Attia Drive, peptides & longevity therapeuticsThe Drive · Peter Attia, MD · Physician · longevity medicineA practicing physician's skeptical, evidence-first walk through the longevity compounds, strong on separating mechanism from marketing.Last checked 2026-06-12

Reference

Authoritative databases, registries, and regulatory tools.

ReferenceFDA Pharmacy Compounding Advisory CommitteeU.S. Food & Drug Administration · FDA / CDERThe committee that decides which peptides may be legally compounded under §503A, the meeting (Jul 23–24, 2026) the catalyst molecules are waiting on.Last checked 2026-06-12 Reference503A Bulk Drug Substances, nominations & statusU.S. Food & Drug Administration · FDAThe actual list that governs what a 503A pharmacy can legally compound. The difference between “removed from Category 2” and “eligible” lives here.Last checked 2026-06-12 ReferenceFederal Register, drug-compounding docketsOffice of the Federal Register · U.S. GovernmentWhere rulemaking actually happens. A favorable PCAC vote is advisory, the binding step is a rule published here.Last checked 2026-06-12 ReferenceWADA Prohibited ListWorld Anti-Doping Agency · WADAThe authoritative source on whether a compound is banned in sport. Several recovery and GH-axis peptides are prohibited, this is how a tested athlete checks.Last checked 2026-06-12 ReferenceClinicalTrials.gov, registry of human studiesU.S. National Library of Medicine · NIH / NLMSearch any compound to see what is actually being tested in humans, by whom, and at what phase, the antidote to anecdote.Last checked 2026-06-12 ReferencePubMed, the primary-literature indexU.S. National Library of Medicine · NIH / NCBIThe front door to the peer-reviewed evidence base. Every grade on this site is anchored to what is (and isn't) indexed here.Last checked 2026-06-12 ReferenceMedlinePlus, plain-language drug & supplement factsU.S. National Library of Medicine · NIHGovernment-run, plain-English reference for approved drugs and common supplements, a neutral second opinion to anything you read here.Last checked 2026-06-12

People

Named researchers and clinicians with a real public track record.

PeoplePredrag Sikirić, the primary BPC-157 investigatorPubMed author profile · Predrag Sikirić, MD, PhD · University of Zagreb · pharmacologyRead the source, not the summary: the researcher whose lab produced most of the BPC-157 evidence. Note how little of it is human.Last checked 2026-06-12 PeopleEric Verdin, NAD+ & ageing biologyBuck Institute for Research on Aging · Eric Verdin, MD · President & CEO, Buck InstituteA leading academic voice on NAD+, useful counterweight to the supplement industry's lifespan claims.Last checked 2026-06-12

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